Upstate South Carolina Vacation Packages

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

Top Upstate South Carolina Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express & Suites Asheville Downtown by IHG

Holiday Inn Express & Suites Asheville Downtown by IHG

2.5 out of 5
per person
Sep 12 - Sep 14
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Asheville (AVL)
9.4/10 Exceptional! (1,013 reviews)
Quick drive to downtown. Friendly staff & clean room.

Reviewed on Jul. 20, 2025

Bluegreen Vacations Blue Ridge Village an Ascend Resort

Bluegreen Vacations Blue Ridge Village an Ascend Resort

3 out of 5
per person
Sep 12 - Sep 14
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Asheville (AVL)
9.2/10 Wonderful! (848 reviews)
Very nice spot, very close to Sugar Mountain

Reviewed on Jul. 16, 2025

The Horton Hotel and Rooftop Lounge

The Horton Hotel and Rooftop Lounge

2.5 out of 5
Downtown Boone Historic District
per person
Sep 12 - Sep 14
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Asheville (AVL)
9.2/10 Wonderful! (136 reviews)
Great stay, great bar. Walking distance from most attractions in Boone. Not far from hiking and Blue Ridge.

Reviewed on Jul. 18, 2025

Sunset Haven

Sunset Haven

4 out of 5
per person
Sep 12 - Sep 14
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Asheville (AVL)
No reviews
Aloft Asheville Downtown

Aloft Asheville Downtown

3 out of 5
Downtown Asheville
per person
Sep 12 - Sep 14
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Asheville (AVL)
9.4/10 Exceptional! (1,008 reviews)
Front desk staff upon checking in were not helpful or friendly. Terrible experience with bartender. Room was clean and comfortable and we enjoyed the pool and view from the pool. The guy working at checkout time was super friendly and that was nice after our poor experience with the other staff.

Reviewed on Jul. 19, 2025

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville which includes autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area
5/5(3 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Ready to book your vacation to Upstate South Carolina?

 

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Upstate South Carolina Hotel Deals

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Jul 27 to Jul 28
CA $153
CA $173 total
Jul 27 - Jul 28
includes taxes & fees
8/10 Very Good! (1,001 reviews)
"Very nice stay"

Reviewed on Jul. 14, 2025

Hilton Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
The price is CA $136 per night from Aug 15 to Aug 16
CA $136
CA $149 total
Aug 15 - Aug 16
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
"My stay was good but several times my key card to inter my room or the pool would not work. That was aggravating. Had to get key card entrance reset, reset, reset . Staff was friendly and helpful."

Reviewed on Jul. 14, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from Jul 28 to Jul 29
CA $101
CA $111 total
Jul 28 - Jul 29
includes taxes & fees
7.2/10 Good! (1,008 reviews)
"Front desk check in clerk was very good,she was friendly and helped me change my room due to noisy kids in room next to me. Myself and several others had difficulty getting our keys to work on the rear entrance. Ice machine on second floor was inoperative."

Reviewed on Jul. 19, 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
See all 2,755 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Upstate South Carolina

Fred W. Symmes Chapel

Fred W. Symmes Chapel

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

Fred W. Symmes Chapel

Greenville Convention Center

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

Greenville Convention Center

Wofford College

Take a campus tour or just explore the area of Wofford College, during your trip to Spartanburg. Experience the area's theater scene or attend a sporting event.

Wofford College

What to do in Upstate South Carolina

Just Desserts Tour In Greenville

Just Desserts Tour In Greenville

CA $109
per adult
Just Desserts Tour In Greenville
Greenville on the Go A 1 Hour Rydable Adventure

Greenville on the Go A 1 Hour Rydable Adventure

CA $81
per adult
Greenville on the Go A 1 Hour Rydable Adventure
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

CA $48
per adult
Paranormal Walking Tour by Greenville Ghost Tours
See all activities in Upstate South Carolina

Frequently asked questions

How much does a Upstate South Carolina vacation package cost?
From as low as CA $936. Yes, you read that right. Our Upstate South Carolina vacation packages are the best way to stretch your budget. Bundle your preferred hotels, flights and rental car and get to know this top destination.
How do I get a cheap travel package to Upstate South Carolina?
Our Upstate South Carolina vacation packages mean plenty of savings for the savvy explorer. For the best deal, simply combine your hotel, flights and extras (such as activities) into one neat package. But great bargains are only the start of your next awesome adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotels around the world to choose from. No matter your style, there's a package with your name on it.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the key things that draws people to Upstate South Carolina, so it makes perfect sense that many opt to stay in Greenville.
What are the top hotels in Upstate South Carolina?
When it comes to hotels in Greenville, Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall are two terrific options. If you're heading to Seneca, Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson will make you feel at home.
How far in advance should I book my Upstate South Carolina vacation?
While prices fluctuate, we generally suggest booking your seats as soon as possible. Most international airfares are available on Expedia up to 12 months in advance. If circumstances have left you booking late, you might still be in luck. Cheap journeys to Upstate South Carolina occasionally appear just weeks before departure.
What does an Expedia Upstate South Carolina travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your ideal Upstate South Carolina travel package. Once you've made your booking, you can add on the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the more dollars you'll save!
What should I know before booking a Upstate South Carolina travel package?
Design deals that suit your budget with an Expedia package. Hotels, flights, rental cars — we're a one-stop shop for all of them. You'll save big bucks just by bundling your bookings. Whether you're embarking on an adventure in the snow or getting some sun on a warm beach, your dream getaway is just a few clicks away.
Can I choose my airline with a Upstate South Carolina Expedia vacation package?
Yes — that's one of the best things about an Expedia vacation package. You can mix and match your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have lots of choice when putting together your Upstate South Carolina getaway.
If I'm not able to travel, can I cancel my Upstate South Carolina vacation package?
Yes, you can cancel your Upstate South Carolina booking if your plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.